Umbilical Cord Blood Lipid Parameters and its Correlation with Birth Weight of Neonates

Introduction: Cardiovascular diseases are the leading cause of mortality in India. The important factor associated is dyslipidemia. A strong relationship has been seen in epidemiological studies between cholesterol and cardiovascular disease. The present study was planned to analyse cord blood lipid profile, apolipoproteins and atherogenic index and to see their relationship with birth weight. Method: Our study group consisted of 300 healthy fullterm newborn. The cord blood was collected immediately after a normal delivery. The blood was tested to determine lipid parameters and was correlated with birth weight. Result: The results showed that the levels of (TC), triglyceride, (HDL) and atherogenic index was higher whereas LDL was lower in high birth weight babies as compared to low birth weight and normal birth weight newborns. The correlation was positive with TC, LDL-Cholesterol, ApoB and atherogenic index but negative with TG, HDL-C and ApoA-1.